Ninety percent of malaria deaths occur in Africa and disproportionately affect pregnant women and young children. Approximately 125 million pregnancies occur each year in areas with P. falciparum and/or P. vivax malaria transmission; 10,000 of these women and 200,000 of their newborns will die as a result of malaria during pregnancy.Malaria in pregnancy (MIP) contributes to maternal anemia, maternal death, stillbirth, spontaneous abortion, and low birth weight.In areas of stable malaria transmission, babies are more likely to be small for gestational age, and in areas of unstable malaria transmission, they are more likely to be born preterm. One-third of all neonatal deaths in malaria endemic regions of Africa are due to low birth weight associated with P. falciparum infections during pregnancy. Key approaches to reduce the burden of malaria for pregnant women, their newborns and young children include: intermittent preventive treatment of pregnant women (IPTp) in areas of stable malaria transmission; use of long lasting insecticide-treated bed nets (ITNs); and, effective case management, including diagnosis, counseling and treatment. Materials contained here include evidenced based technical and programmatic resources to country level implementation and scale up.